Preliminary Agenda

Thursday, September 7, 2023

7:00 AM Breakfast

SESSION 1
Retinopathy of prematurity (ROP): Translation to treatment
Session Moderators: Eric Nudleman, Carina Slidsborg

8:00 AM Pathophysiology of ROP: Basic understanding, controversies and future
Mary Elizabeth Hartnett

8:08 AM HIF in ROP Management
Jonathan Sears

8:16 AM Mechanism of Fibrosis in a Mouse Model of Advanced Retinopathy of Prematurity
Eric Nudleman

8:24 AM Dipeptide Supplement in ROP
Maria Grant

8:32 AM ROP 3 and 4 Studies
Baker Hubbard

8:40 AM Clinical Trial Presentation: FIREFLEYE
Andreas Stahl

8:48 AM Treatment: Laser and Anti-VEGF Considerations highlighting RAINBOW study
Domenico Lepore

8:56 AM Effect of Intravitreal Aflibercept Versus Laser Photocoagulations for Retinopathy of Prematurity: Results from the Phase 3 BUTTERFLEYE Trial
Darius Moshfeghi

9:04 AM Safety Issues with anti-VEGF
Wei-chi Wu

9:12 AM Panel Discussion: ROP and Laser and anti-VEGF treatment
Moderator: Gil Binebaum, Domenico Lepore
Panelists: Baker Hubbard, Amy Hutchinson, Hai Lu, Andreas Stahl

9:37 AM Rapid Fire Presentations
Moderator: Eric Nudleman

1. A Meta-analysis of Neurodevelopmental Outcomes Following Intravitreal Bevacizumab for the Treatment of Retinopathy of Prematurity. Presented by Abed Baiad.
2. A Multicenter Study of Retinopathy of Prematurity Follow-Up Adherence. Presented by Monica Khitri.
3. Elucidating the Role of MEMO1 in VEGF-Triggered Signaling in Retinal Microvascular Endothelial Cells. Presented by Aniket Ramshekar.
4. Vascularization Into the Peripheral Avascular Retina Accelerated Following Single Intravitreal Bevacizumab (0.25 mg) Compared to Age- and Birthweight-Matched ROP Controls. Presented by Lydia Sauer.
5. The Incidence and Timing of Treatment-Requiring Retinopathy of Prematurity (ROP) in the United States: A Multicenter, Retrospective, National Cohort Study. Presented by Shannon Scarboro.
6. Re-treatment Rates and Characteristics of Infants With Severe Retinopathy of Prematurity After Treatment With Bevacizumab: Real-World Experience. Presented by Nasrin Tehrani.
7. Neurodevelopmental Outcomes After Anti-Vascular Endothelial Growth Factor for Retinopathy of Prematurity. Presented by Irena Tsui.

10:40 AM Break and Poster Session

SESSION 2
International ROP

10:55 AM Panel Discussion: International ROP
Moderators: R.V. Paul Chan and Maria Ana Castellanos
Panelists: Hai Lu, Anand Vinekar

SESSION 3
Pearls of Pediatric Retina Surgery

11:20 AM Introduction of Keynote Speaker
Mary Elizabeth Hartnett

11:25 AM Keynote Presentation: Late Challenges in Pediatric Retinal Surgery
George Caputo

12:10 PM Lunch and Exhibits

12:55 PM Poster Session with Dessert and Coffee

SESSION 4
Pediatric Retina Surgery
Session Moderators: Michael Shapiro, Julia Shulman

1:25 PM Familial exudative vitreoretinopathy
Hiroyuki Kondo

1:33 PM Persistent fetal vasculature
Atchara Amphonphruet

1:41 PM Vitreoretinal Management in Non Accidental Trauma NAT
Armie Harper

1:49 PM Management of foveal sub ILM hemorrhages in shaken babies
Fanny Nerinckx

1:57 PM Retinal detachment in kids
Shunji Kusaka

2:05 PM Stickler syndrome
Polly Quiram

2:13 PM Panel Discussion: Pediatric Retina Surgery
Moderators: Fanny Nerinckx, Sui-Chien Wong
Panelists: Miriam A. Al-Feky, Atchara Amphonphruet, Michael Blair, Frank Brodie, Armie Harper, Polly Quiram

2:38 PM Rapid Fire Presentations
Moderator: Alice Lyon

1. Lens Sparing Surgery for Retrolental Stalk in Persistent Fetal Vasculature. Presented by Thibaut Chapron.
2. Laser Prophylaxis for Retinal Detachment in Stickler Syndrome (LePRDS): a Systematic Review and Meta-analysis. Presented by Amir Hajrasouliha.
3. Clinical Characteristics and Surgical Outcomes of Pediatric Idiopathic and Secondary Macular Epiretinal Membrane. Presented by Jinghua Liu.
4. Surgical Results in Patients With Stage 5 Retinopathy of Prematurity. Presented by Alejandro Ortega Desio.
5. Short-Term Perfluorocarbon Liquid Tamponade in Familial Tamponade in Short-Term PerfluorocarbonLiquid Tamponade in Familial Exudative Vitreoretinopathy Associated Rhegmatogenous Retinal Detachment with Severe Proliferative Vitreoretinopathy. Presented by Prithviraj U.
6. Oculocardiac Reflex During Intravitreal Injection of Antiangiogenic in Premature Infants. Presented by Alejandra Pando Cifuentes.

3:26 PM Break and Posters

SESSION 5
Imaging and Other Pediatric Retina Conditions and ROP
Session Moderators: Michelle Cabrera, Adrienne Scott

3:41 PM Incontinentia pigmenti
Pete Campbell

3:49 PM Sickle cell and hemoglobinopathies
Adrienne Scott

3:57 PM Pediatric foveal development
Xi Chen

4:05 PM Universal screening for kids
Darius Moshfeghi

4:13 PM OCT in vitreous
Michelle Cabrera

4:21 PM Panel Discussion: Imaging and Other Pediatric Retina Conditions and ROP
Moderator: Irena Tsui, Wei-Chi Wu
Panelists: Hiroyuki Kondo, Emmanuel Chang, Carina Slidsborg, Michelle Cabrera, Nimesh A. Patel

4:46 PM Rapid Fire Presentations
Moderator: Anand Vinekar

1. Persistent “Pseudo-Plus” Disease in Infants Treated for Retinopathy of Prematurity: Clinical Characteristics and Systemic Disease Associations. Presented by Emily Eton.
2. Preliminary Evaluation of Pediatric Wide-field Fundus Photos Using Artificial Intelligence. Presented by Stephanie Hsu.
3. Assessing the Utility of Handheld Optical Coherence Tomography Imaging in the Management of Clinical Stage 4A Retinopathy of Prematurity. Presented by Shwetha Mangalesh.
4. Eye Versus Computer: Can OROP Softer Help Us in the Diagnosis and Treatment for ROP Zone 1? Presented by Ana Oros.
5. Oxygen-Associated Retinopathy: Case Series. Presented by Paulina Ramirez Neria.
6. Early Postnatal Hyperglycemia Is a Risk Factor for Retinopathy of Prematurity Treatment. Presented by Carina Slidsborg.
7. Efficacy of Smartphone-Based Telescreening for Retinopathy of Prematurity With and Without Artificial Intelligence. Presented by Benjamin Young.

6:00 PM Welcome and Networking Reception

Friday, September 8, 2023
7:00 AM Breakfast

SESSION 6
Tumors
Session Moderator: Prithvi Mruthyunjaya

8:00 AM Retinoblastoma
Scott Oliver

8:08 AM Von hippel-lindau
Emmanuel Chang

8:16 AM Session 6 Panel Discussion: Diagnostic Dilemmas
Moderator: Prithvi Mruthyunjaya
Panelists: Emmanuel Chang, Scott Oliver

SESSION 7
8:46 AM In honor of Michael T. Trese, MD
Mary Elizabeth Hartnett to introduce Polly Quiram

8:51 AM Tribute to Mike T. Trese: Polly Quiram, Hugo Quiroz, Kim Drenser video, Keynote Speaker Introduction

9:36 AM Keynote Presentation: Philosophical considerations in the pediatric vitreoretinal retinal surgery
Antonio Capone, Jr.

10:21 AM Rapid Fire Presentations
Moderator: Hugo Quiroz

1. Macular Sensitivity Improvement on Microperimetry After Voretigene Neparvovec Treatment for Biallelic RPE65-Mediated Retinal Dystrophy. Presented by Sulaiman Alsulaiman
2. Treatable Blindness and Neuroretinal Changes in Patients With Very Rare SLC52A2 Mutation. Presented by Maja Kostic.
3. Assessing Barriers to Genetic Testing in Children With Inherited Retinal Diseases. Presented by Angela Li.
4. The Incidence and Timing of Treatment-Requiring Retinopathy of Prematurity (ROP) in Five Categories of Birthweight and Gestational Age Across the United States. Presented by Cameron Mitchell.
5. Rapid Identification of Phased Variants in Inherited Retinal Disease Patients Using Targeted Long-Read Sequencing. Presented by Debarshi Mustafi.

SESSION 8
Inherited Retinal Diseases and Gene Therapy
Session Moderator: Robert Sisk

11:01 AM Technique and optical coherence tomography
Lejla Vajzovic

11:10 AM Complications
Aaron Nagiel

11:19 AM Inherited Retinal Diseases and Clinical Trials
Robert Sisk

11:28 AM Animal models of inherited retinal diseases
Arlene Drack

11:37 AM X-linked Retinoschisis
Paul Sieving

11:46 AM Electroretinography Simplified
Ramiro Maldonado

11:55 AM Panel Discussion: Inherited Retinal Diseases and Gene Therapy
Moderator: Paul Sieving
Panelists: Arlene Drack, Rachel Huckfeldt, Ramiro Maldonado, Marc Matthias, Aaron Nagiel, Lejla Vajzovic

12:20 PM Wet Lab Introduction and Overview

12:30 PM Lunch and Exhibits

1:30 PM Poster Session and Dessert and Coffee

SESSION 9
Wetlab

1:50 PM Wetlab Rotations

5:00 PM Meeting Adjourns

6:30 PM Dinner Transportation to Stanford Faculty Club

7:00-10:00 PM Gala Dinner at Stanford Faculty Club

Saturday, September 9, 2023
7:00 AM Breakfast

SESSION 10
Myopia
Session Moderator: Arlene Drack, Julia Shulman

8:00 AM Introducation of Keynote Speaker
Lejla Vajzovic

8:05 AM Keynote Presentation: How Retinal Pathways Contribute to Myopic Eye Growth
Machelle Pardue

8:50 AM Clinical trials on prevention of myopia
Margaret Overstreet

8:58 AM Peripheral defocus on myopia
Jay Neitz and Maureen Neitz

9:06 AM Genetics in inherited myopia especially at risk for retinal detachment
Alina Dumitrescu

9:14 AM Panel Discussion: Myopia
Moderators: Alice Lyon, Michael Shapiro,
Panelists: Emmanuel Chang, Alina Dumitrescu, Baker Hubbard

9:39 AM Rapid Fire Presentations
Moderator: Julia Shulman

1. Adoption of Telemedicine for ROP Amongst NICU Directors: Understanding Current Trends, Attitudes, and Future Directions. Presented by Emily Cole.
2. Slit-Lamp Pattern Scan Laser Photocoagulation Guided by Angiography: A Promising Approach for Treating Retinopathy of Prematurity. Presented by M. A. Martínez-Castellanos.
3. Refractive and Visual Outcomes up to 5 Years of Age of Macular Edema of Prematurity Detected by Handheld Spectral-Domain Optical Coherence Tomography. By Jolan Wu.
4. Semi-Automated Analysis of Dome-Shaped Macula in Premature and Full-Term Infants Using Handheld Swept-Source Optical Coherence Tomography. Presented by Joshua Dang.
5. Epidemiology of Inherited Retinal Diseases in the United States: IRIS Registry (Intelligent Research In Sight) Analysis. Presented by Ahmad Al-Moujahed.

10:27 AM Break, Exhibits and Poster Session

SESSION 11
10:49 AM Coats’ Disease in gratitude to the Jack McGovern Coats’ Disease Foundation
Lejla Vajzovic

Session Moderators: J. Michael Jumper, Franco Recchia

10:54 AM Laser in Coats’ disease
Franco Recchia

11:02 AM When to use surgery and how to avoid disaster
J. Michael Jumper

11:10 AM Other medical considerations in Coats’
Aparna Ramasubramanian

11:18 AM Panel Discussion: Coats’ Disease
Moderators: Eric Nudleman
Panelists: Thomas Lee, Mary Elizabeth Hartnett, Lejla Vajzovic,

11:43 AM Rapid-Fire Presentations
Moderator: Thomas Lee

1. Resolution of Massive Subretinal Yellowish Hard Exudate Secondary to Coats’ Disease After Anti-VEGF and Laser Photocoagulation: A Single Case Report Study. Presented by Peranut Chotcomwongse.
2. Incidence and Risk Factors for Exudative Retinal Detachment Following Laser Photocoagulation for ROP. Presented by Devin Cohen.
3. Norrin Translocates to the Nucleus to Activate WNT-Independent Cellular Functions. Presented by Ahmed Elsehemy.
4. Foveal Degradation and Macular Hole in Coats’ Disease. Presented by Tso-Ting Lai.
5. Anatomical Outcomes of Chandelier-Assisted External Drainage for Globe Salvage in Advanced Coats’ Disease. Presented by Simar Rajan Singh.
6. The Effect of FZD4 Agonist Versus Anti-VEGF on Restoration of the Blood-Retina Barrier Function in Murine Disease Models. Presented by Lingling Zhang.

12:46 PM Meeting Wrap Up and Adjournment

*Times, sessions and faculty subject to change.